Evertor
consists of an active ingredient known as Everolimus which is intruded with the
growth of cancer cell and the process is slowed down. Evertor tablets is not a
curable medication, which helps to slow their spreading into the body. If you
need any kind of medicine then you can contact Medatdoorstep. It delivers you
online medicine in Dehradun.
MECHANISM
Everolimus
is an inhibitor of mTOR, joins at high compatibility to FK506 binding protein
12, via producing drug complex that inhibits the production of mTOR. This
inhibition reduces the activity of effectors downstream, which may lead to
stoppage of cell progression from G1 into S phase Finally causes cell growth
arrest and apoptosis
INDICATION
OF EVERTOR
Primarily
Evertor tablets indicated for the treatment:
Kidney
carcinoma
Breast
carcinoma
Brain
carcinoma
Everolimus
is also indicated in various advanced-stage cancer in stomach, intestines or
pancreas.
DOSAGE
REGIMEN OF EVERTOR
In breast
cancer, renal cell cancer, pancreatic cancer, Neuroendocrine cancer:
The prescribed dosage is 10mg should be taken
as a single dose.
In Brain or intracranial cancer:
The prescribed dosage of Evertor as a single the dose is 4.5mg/m2 given orally
In pediatric:
The pediatric dosage of Evertor as a single
dose in the brain or intracranial tumor is 4.5mg/m2 should be given orally.
DRUG-DRUG
INTERACTION
Evertor
interaction with strong inhibitor of CYP3A4, P-GP, causes reducing the efflux
of Everolimus and high plasma concentration of Everolimus. Interaction of Evertor
with strong CYP3A4 inducers will increase the disclosure of Everolimus.
Combination of Evertor with cyclosporine will increase the AUC level of
Everolimus frequently. Combination ketoconazole with Evertor tablet or other
CYP3A4 inhibitors will increase the plasma concentration and AUC of Everolimus.
PREGNANCY
AND LACTATION
Pregnancy
category of Everolimus In patients Evertor is used only after knowing the
benefits to the mother exceed the risk to the fetus. Breastfeeding should not
be suggested
SIDE
EFFECTS
Hypersensitivity
reactions, Lymphomas & other malignancy, Serious infections, Kidney graft
thrombosis, Hepatic artery thrombosis, Nephrotoxicity, Hyperlipemia,
Angioedema, Interstitial lung disease, Thrombocytopenia, Male infertility,
Proteinuria, New commencement of diabetes.
STORAGE
AND HANDLING
Evertor
tablet store at 25°C Store the medicine away from moisture, heat, and light
MISSED
DOSE
Whenever the patient missed a dose, the patient must consult with a medical practitioner and
follow the instructions given by them.
So that a missed dose should be avoided and follow your regular dose as before.
You can
contact Medatdoorstep for Online Medicine Delivery in Dehradun and for more
information email us at medatdoorstepind@gmail.com
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