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Evertor 10mg Tablet- USES, DOSAGE and SIDEEFFECTS - Medatdoorstep


Evertor consists of an active ingredient known as Everolimus which is intruded with the growth of cancer cell and the process is slowed down. Evertor tablets is not a curable medication, which helps to slow their spreading into the body. If you need any kind of medicine then you can contact Medatdoorstep. It delivers you online medicine in Dehradun.

MECHANISM
Everolimus is an inhibitor of mTOR, joins at high compatibility to FK506 binding protein 12, via producing drug complex that inhibits the production of mTOR. This inhibition reduces the activity of effectors downstream, which may lead to stoppage of cell progression from G1 into S phase Finally causes cell growth arrest and apoptosis

INDICATION OF EVERTOR
Primarily Evertor tablets indicated for the treatment:
Kidney carcinoma
Breast carcinoma
Brain carcinoma
Everolimus is also indicated in various advanced-stage cancer in stomach, intestines or pancreas.


DOSAGE REGIMEN OF EVERTOR
In breast cancer, renal cell cancer, pancreatic cancer, Neuroendocrine cancer:
 The prescribed dosage is 10mg should be taken as a single dose.
 In Brain or intracranial cancer:
 The prescribed dosage of Evertor as a single the dose is 4.5mg/m2 given orally
 In pediatric:
 The pediatric dosage of Evertor as a single dose in the brain or intracranial tumor is 4.5mg/m2 should be given orally.


DRUG-DRUG INTERACTION
Evertor interaction with strong inhibitor of CYP3A4, P-GP, causes reducing the efflux of Everolimus and high plasma concentration of Everolimus. Interaction of Evertor with strong CYP3A4 inducers will increase the disclosure of Everolimus. Combination of Evertor with cyclosporine will increase the AUC level of Everolimus frequently. Combination ketoconazole with Evertor tablet or other CYP3A4 inhibitors will increase the plasma concentration and AUC of Everolimus.

PREGNANCY AND LACTATION
Pregnancy category of Everolimus In patients Evertor is used only after knowing the benefits to the mother exceed the risk to the fetus. Breastfeeding should not be suggested

SIDE EFFECTS
Hypersensitivity reactions, Lymphomas & other malignancy, Serious infections, Kidney graft thrombosis, Hepatic artery thrombosis, Nephrotoxicity, Hyperlipemia, Angioedema, Interstitial lung disease, Thrombocytopenia, Male infertility, Proteinuria, New commencement of diabetes.

STORAGE AND HANDLING
Evertor tablet store at 25°C Store the medicine away from moisture, heat, and light

MISSED DOSE
Whenever the patient missed a dose, the patient must consult with a medical practitioner and follow the instructions given by them.
So that a missed dose should be avoided and follow your regular dose as before.
You can contact Medatdoorstep for Online Medicine Delivery in Dehradun and for more information email us at medatdoorstepind@gmail.com

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